Tuesday, 29th July
21st International Conference on Biological Inorganic Chemistry 2025
Days
Monday, 28th July
Tuesday, 29th July
Wednesday, 30th July
Thursday, 31st July
Friday, 1st August
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Speakers
Registration Opens
7:30AM - 6:00PM
Tuesday, 29th July
Terrace Theatre Foyer
Plenary Session 3 - Miguel Costas
8:30AM - 9:15AM
Tuesday, 29th July
Terrace Theatre
Stereoselective Oxidations with Minimalistic Models of Oxygenases
-
Miquel Costas
C-H Bond Cleavage 1.0
9:30AM - 11:00AM
Tuesday, 29th July
Seeing copper enzymes in their native membrane environment
-
Amy C. Rosenzweig
Discovery and study of non-heme Fe radical halogenases
-
Michelle Chang
Electrostatic Effects in Fe-Mediated C—H Oxidation
-
Teera Chantarojsiri
Elucidating Reaction Mechanisms of Coupled Binuclear Copper Enzymes by Correlating QM/MM Calculations, Spectroscopy, and Kinetics
-
Lubomír Rulíšek
Synthetic Systems 1.0
9:30AM - 11:00AM
Tuesday, 29th July
Nickel-containing iron-sulfur clusters: chemistry relevant to CO dehydrogenase active sites
-
Patrick Holland
Tungsten complexes as mimics for acetylene hydratase
-
Nadia C. Mösch-Zanetti
Manganese(III), nature's highest-potential oxidant
-
David C Lacy
Acrylate Synthesis from Ethylene and CO
2
at Ambient Conditions Using a Titanium Complex
-
Changho Yoo
Mo 1.0
9:30AM - 11:00AM
Tuesday, 29th July
On the mechanism of action of formate dehydrogenases
-
Russ Hille
The Molybdenum Cofactor and Pyranopterin Mo Enzyme Catalysis
-
Martin Kirk
Molybdenum cofactor model reveals remarkable redox activity at both molybdenum and the pyranopterin dithiolene ligand
-
Sharon Josephine Nieter Burgmayer
Exploring the catalytic reaction and application of molybdenum-containing formate dehydrogenase
-
Silke Leimkuehler
Artificial 1.0
9:30AM - 11:00AM
Tuesday, 29th July
Site-specific histidine aza-Michael addition in proteins enabled by a ferritin-based metalloenzyme
-
Yane-Shih Wang
How To Control Outer-Sphere Solvent Reorganization Energy to Influence the Reactivity of Metalloenzymes?
-
Saumen Chakraborty
Directed Evolution of Rhodium-Linked Artificial Metalloenzymes with with a Chimeric Protein Scaffold
-
Akira Onoda
Reconstituted Hemoprotein as an Artificial Metalloenzyme Catalyzing Olefin Cyclopropanation
-
Koji Oohora
Development and application of PQQ-dependent artificial metalloenzymes
-
Lisa Olshansky
Fe-Thiolate Chemistry 1.0
9:30AM - 11:00AM
Tuesday, 29th July
CooA forms a variable hydrogen bonding network involving its proximal thiolate ligand: comparison to cytochrome P450 and implications for the ligand switching heme proteins
-
Judith N Burstyn
The active site structural changes in P450/P420 forms of CYP121
-
Piotr Mak
Engineering peroxygenase activity into cytochrome P450 enzymes for selective C-H bond hydroxylations
-
Stephen G Bell
The Role of Thiolates in Creating More Reactive Iron Dioxygen Intermediates
-
Julie A Kovacs
Morning Coffee Break
11:00AM - 11:30AM
Tuesday, 29th July
Seaside Pre-function & Lobby area
Bioinspired Complexes 1.0
11:30AM - 1:00PM
Tuesday, 29th July
New turns in bioinspired dicopper/dioxygen chemistry
-
Franc Meyer
High spin clusters to emulate enzymatic cofactors
-
Theodore Betley
Tetrahedrally Coordinated Copper(II) in Zeolitic Imidazole Frameworks for Enhanced Oxidation Catalysis: Mimicking Superoxide Dismutase and Laccase
-
Yutaka Hitomi
Bioinspired Approaches Toward Activation of Redox-Resistant Substrates
-
Youngmin You
Heme Biology 3.0
11:30AM - 1:00PM
Tuesday, 29th July
An extended network for regulation of heme homeostasis in cells
-
Emma Raven
Structure and function of ancestral class II chelatases in metal-tetrapyrrole biosynthesis toward an understanding of chelatase diversity and evolution
-
Takashi Fujishiro
Porphyrin Selectivity and Rotation in the Mechanism of Coproheme Decarboxylase
-
William N Lanzilotta
Biophysical and Biomedical Analysis of the Metabolite Accumulation in the Heme Group Biosynthetic Pathway
-
Oscar Millet
Co-Enzymes 1.0
11:30AM - 1:00PM
Tuesday, 29th July
Metal Complexes of Modified Porphyrinoids for Selective Photodynamic Inactivation of Pathogens and Tumor Theranostics
-
Janusz M. Dabrowski
The corrinoid model illuminates vitamin-sharing interactions in microbiomes
-
Michiko E Taga
Cobalamin in Motion: Visualizing Catalytic Intermediates of Methionine Synthase
-
Markos Koutmos
The structural enzymology of vitamin B
12
trafficking
-
Romila Mascarenhas
Past and Future Chairs Symposium 1.0
11:30AM - 1:00PM
Tuesday, 29th July
Bioinorganic Strategies to Study Multiple Facets in Alzheimer's Disease
-
Mi Hee Lim
Theta Ribozymes, a New Subfamily of HDV-like Ribozymes Processing tRNAs and Recoding Gut Bacteriophages by the Help of Mg(II) and pH
-
Roland KO Sigel
Lipids as biological targets of isatin-derivatives copper(II) complexes with anticancer activity
-
Ana Maria da Costa Ferreira
Using Potentiometric Titration to Decipher Metallation Pathways of Metallothioneins – Its Use and Limitations
-
Eva Freisinger
Fe-Thiolate Chemistry 2.0
11:30AM - 1:00PM
Tuesday, 29th July
Alternative Oxidative Pathways for Guanitrypmycin Assembly by the Cytochrome P450 GutD
-
Tom Makris
Air-stable Heme Alkylthiolate Complex with Hydrophobic Distal Cavity as a Model of Cytochrome P450
-
Hiroshi Fujii
Modeling Axial Ligand Effects in Bioinspired Reactivity Landscapes of Mid-valent Heme-oxygen and Heme-nitrogen oxide Intermediates
-
Gayan B Wijeratne
Investigating P450s from biarylitide biosynthesis pathways
-
Max J Cryle
Lunch Break
1:00PM - 2:30PM
Tuesday, 29th July
Poster Session 2
2:30PM - 3:30PM
Tuesday, 29th July
Afternoon Coffee Break
2:30PM - 3:30PM
Tuesday, 29th July
Seaside Pre-function & Lobby area
C-H Bond Cleavage 2.0
3:30PM - 5:00PM
Tuesday, 29th July
C-H activation and oxidation with bioinspired copper complexes
-
Ivan Castillo
Thermodynamic principles for regulating of H-atom transfer reactivity and selectivity
-
Martin Srnec
High-valent Metal-Fluoride Complexes for C–H Activation and Fluorination
-
Aidan McDonald
Deciphering the fate of radical intermediates in the catalytic cycles of noncanonical iron-oxo in non-heme iron enzymes
-
Wei-chen Chang
Fe-Thiolate Chemistry 3.0
3:30PM - 5:00PM
Tuesday, 29th July
Mutation-Free Oxidation of Non-Native Substrates by Cytochrome P450BM3: Exploiting Decoy Molecules for Whole-Cell Biocatalysis and Active Site Characterization by X-ray Crystallography
-
Osami Shoji
De Novo
designed thiolate heme proteins as models for cyt P450 monooxygenases and peroxygenases
-
Anabella Ivancich
Quantification of the Thiolate Push Effect in Cyt. P450s Using Nitric Oxide as a Probe
-
Nicolai Lehnert
From shining light on Cytochromes P450 to the “dark side”
-
Lionel Cheruzel
Metalloprotein 2.0
3:30PM - 5:00PM
Tuesday, 29th July
Prediction, Design, and Characterization of Metal Coordination Sites in Proteins Using Metal-Installer
-
Woon Ju Song
Structures of the monomeric and dimeric forms of nitric oxide reductases
-
Takehiko Tosha
Supramolecular chemistry in the biological discrimination of lanthanides
-
Joseph A. Cotruvo, Jr.
O
2
- and H
2
O
2
-tolerant [FeFe] hydrogenases: enzymes that challenge convention
-
Alexey Silakov
Past and Future Chairs Symposium 2.0
3:30PM - 5:00PM
Tuesday, 29th July
Siderophore-anchored artificial metalloenzymes
-
Anne K Duhme-Klair
Cellular distributions of plecstatin and its Os and Ir analogues: EXAFS explains why these are similar, and also highlights how dimers of the broader compound class may be important drug targets.
-
Hugh H Harris
Metalloenzyme Inspired Copper(I)-O
2
Coordination Chemistry
-
Kenneth D Karlin
A very short journey exploring
de novo
designed mononuclear metalloproteins
-
Vincent Pecoraro
Metals in Medicine 1.0
3:30PM - 5:00PM
Tuesday, 29th July
Induction of Immunogenic Cell Death by Metal Complexes
-
Wee Han Ang
Organorhodium complexes of bidentate anticancer ligands with improved drug-like properties to target multidrug resistant cancer
-
Éva A. Enyedy
Copper(II)
N,N,O
-chelating anticancer agents: interaction with proteins combining experimental and computational tools.
-
Oscar Palacios
Mode of action of anticancer gold drugs in A2780 ovarian cancer cells revealed by a multiomics approach
-
Luigi L Messori
Disruption of zinc homeostasis as a possible factor in SOD1 aggregation relevant to ALS pathogenesis
-
Yoshiaki Furukawa
Plenary Session 4 - Amy Palmer
5:15PM - 6:00PM
Tuesday, 29th July
Terrace Theatre
Illuminating the cell biology of zinc
-
Amy E Palmer
Editor in Chief of Science Magazine Roundtable
6:00PM - 7:00PM
Tuesday, 29th July
Terrace Theatre Foyer
Title coming soon
-
Alison Butler
Title coming soon
-
Harry Gray
Looking back and forward: the bright future of bioinorganic chemistry
-
Holden Thorp
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