Invited Talk 21st International Conference on Biological Inorganic Chemistry 2025

High spin clusters to emulate enzymatic cofactors (122009)

Theodore Betley 1
  1. Harvard University/CCB, Cambridge, MA, United States

We report the synthesis and characterization of high spin iron hydride clusters and their reactivity to undergo hydride transfer catalysis. The cluster makeup allows for stabilization of traditionally unstable intermediates. We will also describe the synthesis of canonical trianionic bridging ligands (e.g. N, P, CH) that assume unusual electronic structures to facilitate bonding between the cluster core and the light atom bridge.