Thursday, 31st July 21st International Conference on Biological Inorganic Chemistry 2025

• Mechanism and dynamics of fatty acid photodecarboxylase - Ilme Schlichting

• Structural and Chemical Dynamics of Photosystem II During Light-Induced Water-Oxidation Reaction - Junko Yano
• Development of Molecular Catalysts for Photosynthetic Reactions - Shigeyuki Masaoka
• Development of functional models of photosystems and seeing the key intermediates in water oxidation process - Young Hyun Hong
• Bio-inspired Electro- and Photocatalysts for Water Oxidation - Galia Maayan

• Nonheme iron activation of O₂: Intermediates, substrate oxidation, and rebound selectivity - David P Goldberg
• Spin State and Reactivity of Enzymatic Ferryl Intermediates in Nonheme Iron Enzymes - Yisong (Alex) Guo
• Mechanistic Studies of the Ethylene-Forming Enzyme - Carsten Krebs
• Do you even own a proton? The awkward spectroscopic quirks of globin-(like) ferryls - Radu Silaghi-Dumitrescu

• Sustainable Catalysis Using Visible Light, Air and Water: Understanding Photocatalysis Through Mechanistic Studies - Rajeev Gupta
• Targeting Ligand Design to Facilitate Oxyanion Reduction with Iron - Alison R Fout
• Repurposing Reductase Chemistry using Synthetic Iron Complexes Containing Secondary Sphere Hydrogen Bonds - Nathaniel Szymczak
• Nitrogen (Re)Cycle: Harnessing the secondary coordination influence for nitrogen oxyanion reduction and the formation of N-N bonds. - John D Gilbertson

• Oxidation Reactivity of Mononuclear Tetrahedral Copper(II) Complexes - Shinobu Itoh
• Model Systems for Investigating Sulfur and Selenium Bioinorganic Chemistry - Mike Pluth
• Spin Interactions in Transition Metal Complexes: Implications for Electrocatalytic Hydrogen Evolution - Junhyeok Seo
• Square-planar Nickel Bis(phosphinopyridyl) Complexes for Long-lived Photocatalytic Hydrogen Evolution - Hua-Fen Hsu

• Electron transfer and electronic conductance in multi-heme cytochromes - Jochen Blumberger
• Designing energetic pathways in metalloporphyrin binding peptide assemblies. - H. Christopher Fry
• Natural and Synthetic Conductive Proteins: from Rock-Breathing Bacteria to Electrocatalytic Materials - Allon I. Hochbaum

Additional speakers include:

Dibya Jyoti Barman - Hydrogen Bond Donor or trans Donor> Spectroscopic Characterization and Reactivity Studies of Ferryl-oxo Intermediates bearing a pendant alcohol moiety

Patrick Sheridan - Designing second-sphere hydrogen bonding interactions in biomimetic models of thiol-oxidizing nonoheme iron enzymens

Jasmine Nehema - Glowing insights: luminescent lanthanide fibre optic sensors for oxidative stress detection

Doreen Reuter - Expanding the Py5 Toolbox: Functionalized Pentapyridine-based ligands for synthetic Iron-Oxido chemistry

• Natural and De Novo Designed bi-functional peroxidases (KatGs): the role of the [Fe(IV)=O Trp^.] intermediates in the intrinsic isoniazid resistance of Mycobacterium abscessus KatG. - Angela S. Gehrckens
• Metal-enhanced salivary peptidomimetics: a dual-modification strategy against multidrug-resistant pathogens - Joanna Wątły

• Capturing One-Carbon Chemistry, One-Structural Snapshot at a Time - Cathy Drennan
• Cobalamin in Motion: Visualizing Catalytic Intermediates of Methionine Synthase - Markos Koutmos
• Metalloenzyme-Mediated Amino Acid Crosslink in Proteins - Aimin Liu
• Redox Partner and Substrate Mediated Allosteric Control in Cytochromes P450 - Thomas Poulos

• Functional models of native and non-native substrates of nitrogenase enzymes - Jonas C Peters
• Enhanced Reactivity in a Dynamic Biomimetic of [Fe]-Hydrogenase: A Synthetic Psychrophile featuring a Flexible ‘Third Coordination Sphere’ - Michael J Rose
• The development of metalloflavin complexes - Yunjung Baek
• Small Molecule Models and Reactivity of the Nickel Pincer Nucleotide (NPN) Cofactor - Louise Berben

• Ferritin-based delivery of metallodrugs - Paola Turano
• The nascent iron mineral core of an H-chain ferritin - Nick E Le Brun
• Ferritin: the ferroxidase reaction revisited - Guy NL Jameson
• Inhibiting the mobilization or iron from bacterioferritin kills Pseudomonas aeruginosa and Acinetobacter baumannii cells - Mario Rivera

• Harnessing redox power: The role of NrfA and NrfH in the dissimilatory nitrate reduction to ammonium (DNRA) pathway - Eric L Hegg
• Functional Diversity and Mechanism of Periplasmic Nitrate Reductase. - Partha Basu
• Unusual Properties of the Nitrous oxide reductase: Mitigation of N₂O (green house gas) - Isabel Moura
• The  Central Role of Nitrate /Nitrite in the N-Cycle - Jose Moura

• A nickel-based organic framework sustains centimeter-scale electron transport in cable bacteria. - Filip JR Meysman
• Investigating Electron Conductivity Regimes within Cytochrome Polymers from First-Principles Modeling - Sahar Sharifzadeh
• Metabolic diversity in the world of biological energy conservation - Kristian Parey

• Metallothioneins as biomarkers in Menkes disease patients - Mercè Capdevila
• Dimers of N-acylhydrazone-containing copper(II) complexes constitute potent antitumor agents: solution chemistry and mechanistic studies in TNBC cells - Nicolás A. Rey
• Nitroprusside-Loaded Silica Nanoparticles: A safer sodium nitroprusside formulation for acute treatment of hypertension - Luiz Gonzaga de França Lopes
• Antitumoral vs. antiparasitic activity of Cu(II) and Zn(II) mixed ligands complexes - Lucia Otero
• Luminescent metal ion complexes for labelling organelles - Sally Plush
• Maneb: The chemistry and neurotoxicity of a manganese-containing pesticide. - Fabian Mohr

• There is more than copper to reducing nitrous oxide - Oliver Einsle
• Delineating hydrocarbon and electron substrate access routes through mutagenesis of the hydroxylase protein of soluble methane monooxygenase - Rahul Banerjee
• Exploring structure-function relationships in alkane monooxygenase (AlkB), the dominant metalloenzyme in the global cycling of liquid alkanes.     - Rachel N Austin
• A panoramic view of the protein space of multiheme cytochromes c and of their evolutionary mechanisms - Ricardo O Louro

• Bio-organometallic NO_x Upcycling Mediated by Multifunctional Metal Catalysts - Yunho Lee
• Organometallic Intermediates in the Wood-Ljungdahl Pathway - Ritimukta Sarangi
• The Organometallic Chemistry of Nickel Enzyme Mimics - Liviu M Mirica
• Mechanistic Study on O₂ Activation by Divalent and Trivalent Organonickel Complexes - Kiyoung Park

• Redox traits and redox-carrier roles in the oxo-acid:ferredoxin oxidoreductase superfamily - Sean J Elliott
• How does haem alter the behaviour of the core clock proteins? - Andrew Hudson
• Uncovering the role of protein structure and dynamics in the regulation of heme biosynthesis - Breann L Brown
• Resonance Raman spectral analysis of cytochrome c oxidase with its positive regulator CHCHD2 - Sachiko YANAGISAWA

• Ferrocene-Estrogen Conjugates as Potential Anti-cancer Drugs for Hormone-Dependent Breast Cancer - Enrique Meléndez
• Synthesis, Characterization, Anticancer and Antibacterial Studies of Ruthenium(II/III) Benzimidazole Complexes - Daphne T Mapolelo
• Highly antitumor-active azolato-bridged dinuclear Pt(II) complexes induce DNA compaction and liquid-liquid phase separation. - Seiji Komeda
• New Studies on Gold-Based Theranostics and Prodrug Activation Strategies - Nils Metzler-Nolte
• Exercise Mimetics in Cancer Therapy: Targeting MMP Expression and Activity - Hyuck Jin Lee

• Cryo-EM of cytochrome nanowires - Fengbin Wang
• Electron bifurcation:  sorting electrons into high and low energy pools without Maxwell’s Demon    - David N Beratan
• Multiheme Cytochromes as Electron Carriers in Bacterial Redox Networks - Ekaterina Pletneva

• Near-inrared light activation of a new ruthenium-based photoactivated chemotherapy agents  - Sylvestre Bonnet
•   Potent photocytotoxicity of ternary thiosemicarbazone complexes of oxovanadium(IV) and copper(II) towards cancer cells - Musa S. Shongwe
• Perturbing the Nucleolus with Platinum Anticancer Compounds - Victoria DeRose
• DNA cleavage and antitumoral activity of zinc(II) and iron(III) complexes with a new phenol-based ligand containing uncoordinated thioether moieties - Rosely Peralta
• Metal Nanoclusters Mediated Non-canonical Fluorescent DNA Structures - Pratik Shah

• Inorganic Chemical Design of Functional Proteins - F. Akif Tezcan